President Joe Biden and Israeli Prime Minister Benjamin Netanyahu spoke on Wednesday, according to the White House.
Vice President Kamala Harris also joined the call, the White House said.
It marked the first phone call between the two leaders in months, and since fighting has intensified in the Middle East as Israel continues its war against Hamas in Gaza while also seeking to root out Hezbollah infrastructure in Lebanon.
White House press secretary Karine Jean-Pierre told reporters the call lasted about 30 minutes and included a “range of issues.”